King's College London
The South London and Maudsley NHS Foundation Trust (SLAM) is the largest provider of mental health services in Europe. The hospital electronic health record (EHR), implemented in 2007, contains records for 250,000 patients in a mixture of structured and over 18 million free text fields.
At the NIHR Biomedical Research Centre for Mental Health and Unit for Dementia at the Institute of Psychiatry, Psychology and Neuroscience (IOPPN), King’s College London we have developed unique capacity through the Clinical Record Interactive Search (CRIS) application which allows research use of the anonymised mental health electronic records data, recently exported as a resource to four other UK mental health providers. CRIS has generated substantial, comprehensive and innovative research output since its development and ethics approval in 2008.
Through the CRIS programme we have developed a suite of natural language processing information-extraction applications covering a range of hitherto-unrealised constructs such as symptomatology, interventions and outcomes (eg. adverse drug reactions). However, much of the information within the record is still hidden from the clinician and researcher. This project will provide semantic annotation and semantic search capability across the complete record with integrated biomedical information extracted from the literature knowledgebase.
Such capability will transform the way clinicians and researchers use the EHR and, through our patient led model of 'consent for contact' for example, will facilitate recruitment into trials.